现在是:
 

顾连峰


  发布时间: 2016-01-13  信息员:  

 

顾连峰

林木生物信息学团队成员:张航晓、赵良真、王永生、王汇源、王慧慧、高宇帮、刘旭庆、徐锡、张泽宇



PI简介:

顾连峰,博士生导师。2012年获得中国科学院生物信息学博士学位,2015年从美国加州大学河滨分校访学回国,受聘为福建农林大学林学中心全职教授。2016年入选福建省C类引进高层次人才,2017年获福建农林大学“金山学者”荣誉称号。以福建农林大学为依托单位主持2015国家自然科学基金面上项目自毒胁迫下杉木可变剪接与microRNA相互调控网络研究”,主持2016年国家重点专项“林木次生生长的分子调控和环境胁迫机制”子课题。在PNASCell ResearchNature genetics权威期刊上发表相关文章20篇。目前主要从事生物信息学林木遗传改良相关研究

实验室网址:www.bioinfor.org

电子邮箱:lfgu@fafu.edu.cn


主要研究领域:开发生物信息学软件解析来自高通量技术所产生的大批量数据,从基因组、转录组和蛋白质组等组学数据中挖掘林木次生生长的规律。结合二代和三代高通量测序及蛋白组学数据开展重要速生树种(毛竹、杉树、杨树和桉树)的基因表达调控网络研究。并深入开展转录后调控网络研究,为林木遗传改良提供理论依据。  

  1. Zhang, H., Lin, C. and Gu, L†. (2016), Light Regulation of Alternative Pre-mRNA Splicing in Plants. Photochem Photobiol. doi:10.1111/php.12680.   († corresponding IF=2.235)

  2. Li S, Zhang G, Zhang X, Yuan J, Deng C, Gu L†, Gao W†.(2016),DPTEdb, an integrative database of transposable elements in dioecious plants. Database Database: baw078 doi:10.1093/database/baw078. († co-corresponding IF=2.627) 

  3. Zhang S, Xu M, Qiu Z, Wang K, Du Y, Gu L, Cui X. (2016), Spatiotemporal transcriptome provides insights into early fruit development of Solanum lycopersicum, Sci. Rep. 6, 23173; doi: 10.1038/srep23173. († co-corresponding IF=5.228)

  4. Wang K*, Jiao Z*, Xu M*, Wang Y, Li R, Cui X, Gu L†, Zhang S†. (2017), Landscape and Fruit Developmental Regulation of Alternative Splicing in Tomato by Genome-wide Analysis Horticultural Plant Journal. († co-corresponding)

  5. Gu L, and Guo R. (2007). Genome-wide detection and analysis of alternative splicing for nucleotide binding site-leucine-rich repeats sequences in rice. J Genet Genomics 34, 247-257. (First-author IF=3.585)

  6. Zhang Y*, Gu, L*, Hou, Y*, Wang L, Deng, X, Hang R, Chen D, Zhang X, Zhang Y, Liu C, and Cao, X.( 2015) Integrative genome-wide analysis reveals HLP1, a novel RNA-binding proteinregulates plant flowering by targeted alternative polyadenylation. Cell research 25, 864-876. (*co first-author IF=14.812)

  7. Wei L*,Gu L*, Song X*, Cui X, Lu Z, Zhou M, Wang L, Hu F, Zhai J, Meyer B, Cao X. (2014) Dicer-like 3 produces transposable element-associated 24-nt siRNAs that control agricultural traits in rice. Proc Natl Acad Sci U S A 111: 3877-3882. (*co first-author IF=9.674)

  8. Deng X*, Gu L*,Liu C*, Lu T*, Lu F, Lu Z, Cui P, Pei Y, Wang B, Hu S, and Cao X. (2010). Arginine methylation mediated by the Arabidopsis homolog of PRMT5 is essential for proper pre-mRNA splicing. Proc Natl Acad Sci U S A 107, 19114-19119. (*co first-author IF=9.771)

  9. Zhou M*, Gu L*, Li P, Song X, Wei L, Chen Z. and Cao X. (2010) Degradome sequencing reveals endogenous small RNA targets in rice (Oryza sativa L. ssp. indica). Front. Biol., 5, 67–90. (*co first-author)

  10. Wang Q*,Zuo Z*,Wang X*,Gu L, Yoshizumi T,Yang,Z,Liu Q,Liu W,Han Y,Liu B, Wohlschlegel J A, Matsui M, Oka Y and Lin C. (2016) Photoactivation and inactivation mechanisms of Arabidopsis cryptochrome2. Science. (IF=34.661)

  11. Yan H, Zhang H, Wang Q, Jian H, Qiu X, Baudino S, Just J, Raymond O, Gu L, Jihua W, Bendahmane M and Tang K (2016). The Rosa chiensis cv. Viridiflora phyllody phenotype is associated with misexpression of flower organ identity genes. Front. Plant Sci. 7:996. doi: 10.3389/fpls.2016.00996 (IF=4.495)

  12. Li C, Gu L, Gao L, Chen C, Wei C, Qiu Q, Chien C, Wang S, Jiang L, Chen C, Yang S, Nguyen V, Snyder M, Burlingame A, Kohalmi S, Huang S, Cao X, Wang Z, Wu K, Chen X, Cui Y. (2016).Concerted genomic targeting of histone H3 lysine 27 demethylase REF6 and chromatin-remodeling ATPase BRM in Arabidopsis. Nature genetics. doi:10.1038/ng.3555. (IF=31.616)

  13. Cui X*, Lu F*, Qiu Q*, Zhou B*, Gu L, Zhang S, Kang Y, Cui X, Ma X, Yao Q, Ma J, Zhang X, Cao X. REF6 recognizes a specific DNA sequence to demethylate H3K27me3 and regulateorgan boundary formation in Arabidopsis. Nature genetics. (2016). doi:10.1038/ng.3556. (IF=31.616)

  14. Deng X*, Lu T*, Wang L*, Gu L, Sun J, Kong X, Liu C, Cao X. (2016). Recruitment of Prp19C/NTC to the activated spliceosome requires AtPRMT5. PNAS. doi:10.1073/pnas.1522458113. (IF=9.423)

  15. Wu, Z*, Zhu D*, Lin X*, Miao L*, Gu L, Deng X, Yang Q, Sun K, Zhu D, Cao X, TSUGE T, Dean C, Aoyama T, Gu H, Qu L. (2016)RNA-binding proteins At RZ-1B and At RZ-1C play a critical role in regulation of pre-mRNA splicing and gene expression during Arabidopsis development. The Plant Cell: TPC2015-00949. (IF=8.538)

  16. Wang L, Song X, Gu L, Li X, Cao S, Chu C, Cui X, Chen X, and Cao X. (2013). NOT2 proteins promote polymerase II-dependent transcription and interact with multiple MicroRNA biogenesis factors in Arabidopsis. Plant Cell 25, 715-727. (IF=9.575)

  17. Cui X, Jin P., Cui X, Gu L, Lu Z, Xue Y, Wei L, Qi J, Song X, Luo M, Gynheung An, Cao X. (2013) Control of Transposon Activity by a Histone H3K4 Demethylase in Rice. Proc Natl Acad Sci U S A. 110(5):1953-1958. (IF=9.809)

  18. Zhang L, Cheng Z, Qin R, Qiu Y, Wang J, Cui X, Gu L, Zhang X, Guo X, Wang D, Jiang L, Wu C, Wang H, Cao X, Wan J. (2012). Identification and Characterization of an Epi-1 allele of OsFIE1 Reveals a Regulatory Linkage between two Epigenetic Marks in Rice. Plant Cell 24, 4407-4421. (IF=9.251)

  19. Wu B, Suo F, Lei W, and Gu, L. (2014), Comprehensive Analysis of Alternative Splicing in Digitalis purpurea by Strand-Specific RNA-Seq. PLoS One 9, e106001. († corresponding IF=3.234)

  20. Zhou H, Zhou M, Yang Y, Li J, Zhu L, Jiang D, Dong J, Liu Q, Gu L, Zhou L., … Cao X, Zhuang C. (2014). RNAase Zs1 processes UBL40mRNA and controls thermo-sensitive genic male sterility in rice. NATURE COMMUNICATIONS. doi:10.1038/ncomms5884 (IF=11.470)