唐定中，教授，博士生导师，国家杰出青年科学基金获得者，福建农林大学植物免疫研究中心主任
1992年武汉大学生物系学士；1995年福建农业大学硕士；1996-1997年英国John Innes Centre访问学者；1998年福建农业大学博士。1998-1999中科院发育所博士后。1999-2006年Indiana大学博士后。2006年入选中科院“百人计划”，2006-2016任中科院遗传与发育生物学研究所研究员和博士生导师，2011-2016任植物细胞与染色体工程国家重点实验室副主任。2015年获国家杰出青年科学基金；2017年入选“国家百千万人才工程”家并被授予“有突出贡献中青年专家”荣誉称号，获国务院“政府特殊津贴”。2017年1月任福建农林大学教授，植物免疫研究中心主任。任Frontiers in Plant Science及Frontiers in Microbiology刊物编委（Associate Editor），Journal of Integrative Plant Biology （JIPB）杂志编委，遗传杂志副主编，中国遗传学会常务理事，福建省遗传学会理事长，中国植物生理与植物分子生物学学会“植物－微生物分子互作”专业委员会副主任，闽台作物有害生物生态防控国家重点实验室副主任。近几年来，作为通讯作者在Nature Communications, PNAS, Plant Cell，Molecular Plant等国际主流学术刊物上发表一系列论文，多次应邀参加国际会议，并作大会报告。主持国家自然科学基金重点、杰青、国际合作等项目和科技部国家重大科学研究计划、国际合作重点及中科院战略性先导等多个课题。主要研究方向为植物与病原菌的分子互作，长期从事植物免疫分子机制及其信号转导途径的研究，系统研究植物与病原菌互作的分子机制。
研究方向：植物与病原菌的相互作用，主要研究植物免疫的分子机制及其信号转导途径
1. 植物免疫的分子机制
利用模式植物拟南芥，采用遗传学，分子生物学以及生物化学的方法，分离和鉴定植物免疫信号通路中的重要组分，研究植物免疫的分子机理。利用拟南芥与白粉菌及假单胞杆菌互作体系，我们在植物免疫分子机制研究中取得了许多进展。例如，我们前期工作发现油菜素甾醇受体BRI1的底物BSK1是免疫受体复合体核心成员，与病原相关分子模式（PAMPs）受体FLS2互作，调控植物的抗病反应（Shi et al., 2013）；发现钙调素结合的转录因子CAMTA3/SR1、26S蛋白亚基RPN1a、THO/TREX蛋白复合体的组分HPR1、细胞自噬蛋白ATG2参与植物的先天免疫反应(Wang et al.，2011；Nie et al., 2012；Pan et al., 2012；Yao et al., 2012)。我们发现植物免疫负调控因子EDR1蛋白激酶精细调控植物抗病性的分子机理（Zhao et al., 2014；Wu et al., 2015；Gao et al., 2020；Chen et al., 2022）;采用遗传学及分子生物学的手段我们还发现免疫模式受体复合体的新成员RLK902和LLG1，并解析了RLK902、LLG1、BSK1及EXO70B1调控植物免疫的分子机理（Shen et al., 2017；Yan et al., 2018；Zhao et al., 2019；Wang W. et al., 2020; Shi et al., 2022； Gao et al., 2024）等。我们在非典型胞内免疫受体（NLR）方面也取得了较多进展，发现非典型NLR蛋白TN2可能监控胞吐复合体成员(Zhao et al., 2015)，而钙依赖蛋白激酶CPK5参与非典型NLR激活的抗性反应（Liu et al., 2017）。此外，还进一步揭示非典型NLR作用机理，发现非典型NLR可与全长NLR形成异源二聚体，参与NLR免疫激活，并发现非典型NLR激活的免疫需要辅助蛋白ADR1参与（Cai et al., 2021; Chen et al., 2021; Wang et al., 2021）,而CPK5磷酸化钙调素转录因子CAMTA3，参与调控非典型NLR蛋白TN2介导的植物免疫（Liu et al., 2024）。这些发现对于深入理解植物免疫机理有重要意义。我们将利用已有的研究基础，进一步解析植物抗病反应的信号转导途径和网络调控机制。
2. 重要作物病害的抗性机制
稻瘟病是水稻生产上最重要的病害，尽管近近年来对稻瘟病的研究已取得了不少成果，克隆了多个稻瘟病抗性基因，然而，对这些抗性基因的作用机制还很不清楚。我们将利用遗传学、细胞生物学、分子生物学及生化的方法，研究水稻与稻瘟菌的分子互作，鉴定和克隆调控稻瘟病抗性的基因以及稻瘟菌中的效应蛋白，阐明水稻调控抗病反应的分子机制，最近我们已获得一些进展( Li et al., 2020; Hou et al., 2020; Yang et al., 2020; Xu et al., 2021; Yang et al., 2021; Yu et al., 2021; Lu et al., 2022, Liu et al., 2022., Liang et al., 2023; Li et al., 2023；Li et al., 2024; Lu et al., 2024, Wang et al., 2024)。小麦白粉病和锈病是小麦生产最主要的病害，由于小麦基因组复杂，目前对小麦病害的研究还很不够。我们将以二倍体小麦祖先种乌拉尔图为基础，利用小麦功能基因组学研究中的最新成果，鉴定具有广谱和持久抗性的小麦白粉病及锈病的抗性基因，为小麦抗病育种中提供重要基因资源。我们最近克隆的白粉病及条锈病抗性新基因为解析小麦抗病机理提供了基础(Zhang et al., 2017; Zou et al., 2018; Wang H. et al., 2020; Xu et al., 2022; Zou et al., 2022) 。
E-mail：dztang@fafu.edu.cn
欢迎有志于植物免疫研究的青年学子报考硕博研究生或到实验室从事博士后研究，并诚招实验室各类工作人员，待遇从优。
PUBLICATIONS (*通讯作者)
2024
Lu L, Fang J, Xia N, Zhang J, Diao Z, Wang X, Liu Y, Tang D*, Li S*. Phosphorylation of the transcription factor OsNAC29 by OsMAPK3 activates diterpenoid genes to promote rice immunity. Plant Cell. 2024 Dec 12:koae320. doi: 10.1093/plcell/koae320.
Wang X, Diao Z, Cao C, Liu Y, Xia N, Zhang Y, Lu L, Kong F, Zhou H, Chen L, Zhang J, Wang B, Huang R, Tang D*, Li S*. The receptor-like cytoplasmic kinase OsBSK1-2 regulates immunity via an HLH/bHLH complex. J Integr Plant Biol. 2024 Dec;66(12):2754-2771. doi: 10.1111/jipb.13783.
Rui L, Kang P, Shao J, Lu M, Cui B, Zhao Y, Wang W, Cai H, Tang D, Loake GJ, Wang M*, Shi H*. The chloroplast-localized casein kinase II α subunit, CPCK2, negatively regulates plant innate immunity through promoting S-nitrosylation of SABP3. Plant J. 2024 Aug 27. doi: 10.1111/tpj.17000.
Gao C#, Zhao Y#, Wang W, Zhang B, Huang X, Wang Y, Tang D*. BRASSINOSTEROID-SIGNALING KINASE 1 modulates OPEN STOMATA 1 phosphorylation and contributes to stomatal closure and plant immunity. Plant J. 2024 Aug 10. doi: 10.1111/tpj.16968.
Li YB, Liu C, Shen N, Zhu S, Deng X, Liu Z, Han LB*, Tang D*. The actin motor protein OsMYA1 associates with OsExo70H1 and contributes to rice secretory defense by modulating OsSyp121 distribution. J Integr Plant Biol.2024 Jul 23. doi: 10.1111/jipb.13744.
Lu L, Zhang J, Zheng X, Xia N, Diao Z, Wang X, Chen Z, Tang D*, Li S*. OsMPK12 positively regulates rice blast resistance via OsEDC4-mediated transcriptional regulation of immune-related genes. Plant Cell Environ. 2024 May 21. doi: 10.1111/pce.14955.
Yu S, Li S, Wang W*, Tang D*. OsCAMTA3 Negatively Regulates Disease Resistance to Magnaporthe oryzae by Associating with OsCAMTAPL in Rice. Int J Mol Sci. 2024 May 6;25(9):5049. doi: 10.3390/ijms25095049.
Wang Z, Yang D, Zhong G, Li S, Wang W*, Tang D*. Nucleotide-binding leucine-rich repeat receptor homologs Pib and PibH8 interact and contribute to immunity in rice. Plant Physiol. 2024 Apr 30:kiae244. doi: 10.1093/plphys/kiae244.
Shen N#, Han L#, Liu Z, Deng X, Zhu S, Liu C, Tang D*, Li Y*. The Microtubule End Binding Protein Mal3 Is Essential for the Dynamic Assembly of Microtubules during Magnaporthe oryzae Growth and Pathogenesis. Int J Mol Sci. 2024 Feb 26;25(5):2672. doi: 10.3390/ijms25052672.
Liu N.#, Jiang X.#, Zhong G.#, Wang W., Hake K., Matschi S., Lederer S., Hoehenwarter W., Sun Q., Lee J.*, Romeis T.*, Tang D.* CAMTA3 repressor destabilization triggers TIR-domain protein TN2-mediated autoimmunity in the Arabidopsis exo70B1 mutant.
Plant Cell.2024 doi: 10.1093/plcell/koae036.
Li Q.#, Shao J.#, Luo M, Chen D, Tang D*, Shi H*.BRASSINOSTEROID-SIGNALING KINASE1 associates with and is required for cysteine protease RESPONSE TO DEHYDRATION 19-mediated disease resistance in Arabidopsis. Plant Sci. 2024 doi: 10.1016/j.plantsci.2024.112033.
Li Y.B.#, Shen N.#, Deng X., Liu Z., Zhu S., Liu C., Tang D.*, Han L.B.*. Fimbrin associated with Pmk1 to regulate the actin assembly during Magnaporthe oryzae hyphal growth and infection. Stress Biol. 2024 4(1):5. doi: 10.1007/s44154-023-00147-5.
2023
Xie B.#, Luo M.#, Li Q, Shao J., Chen D., Somers D.E., Tang D.*, Shi H.* NUA positively regulates plant immunity by coordination with ESD4 to deSUMOylate TPR1 in Arabidopsis.New Phytologist 2023 https://doi.org/10.1111/nph.19287
Li S.*, Xiang X. , Diao Z., Xia N., Lu L., Zhang J., Chen Z., Tang D.*. The OsBSK1-2-MAPK module regulates blast resistance in rice. Crop Journal. 2023, doi：10.1016/j.cj.2023.11.009
Liang J,. Lu L., Zhou H., Fang J., Zhao Y., Hou H., Chen L., Cao C., Yang D., Diao Z., Tang D., Li S.*. Receptor-like kinases OsRLK902-1 and OsRLK902-2 form immune complexes with OsRLCK185 to regulate rice blast resistance. J Exp Bot. 2023. doi: 10.1093/jxb/erad460.
Zou S., Xu Y., Li Q., Wei Y., Zhang Y., Tang D*. Wheat powdery mildew resistance: from gene identification to immunity deployment. Front Plant Sci. 2023. doi: 10.3389/fpls.2023.1269498.
Wang W#, Chen S#, Zhong G#, Gao C, Zhang Q, Tang D*. MITOGEN-ACTIVATED PROTEIN KINASE3 enhances disease resistance of edr1 mutants by phosphorylating MAPKKK5. Plant Physiol. 2023 doi: 10.1093/plphys/kiad472.
Zhong G., Chen Y., Liu S., Gao C., Chen R., Wang Z., Wang W*, Tang D*. EDR1 associates with its homologs to synergistically regulate plant immunity in Arabidopsis. Plant Sci. 2023 doi: 10.1016/j.plantsci.2023.111619
Liu J*, Tang D. Plant immunity research in China. Phytopathology Research. 2023. 5:37doi: 10.1186/s42483-023-00196-8
2022
Shi H*, Li Q, Luo M, Yan H, Xie B, Li X, Zhong G, Chen D, Tang D*. BRASSINOSTEROID-SIGNALING KINASE1 modulates MAP KINASE15 phosphorylation to confer powdery mildew resistance in Arabidopsis. Plant Cell. 2022, 34(5):1768-1783. doi: 10.1093/plcell/koac027.
Zou S, Shi W, Ji J, Wang H, Tang Y, Yu D, Tang D*. Diversity and similarity of wheat powdery mildew resistance among three allelic functional genes at the Pm60 locus.
Plant Journal.2022 doi: 10.1111/tpj.15771.
Lu L#, Diao Z#, Yang D, Wang X, Zheng X, Xiang X, Xiao Y, Chen Z, Wang W, Wu Y, Tang D*, Li S*. The 14-3-3 protein GF14c positively regulates immunity by modulating the protein homoeostasis of the GRAS protein OsSCL7 in rice. Plant Cell & Enviroment. 2022. doi: 10.1111/pce.14278.
Chen R, Sun P, Zhong G, Wang W, Tang D*. The RECEPTOR-LIKE PROTEIN53 immune complex associates with LLG1 to positively regulate plant immunity. J Integr Plant Biol. 2022; 64(9):1833-1846. doi: 10.1111/jipb.13327.
Gao C, Tang D, Wang W*. The Role of Ubiquitination in Plant Immunity: Fine-Tuning Immune Signaling and Beyond. Plant Cell Physiol. 2022; 63(10):1405-1413. doi: 10.1093/pcp/pcac105.
Zou S#, Tang Y#, Xu Y, Ji J, Lu Y, Wang H, Li Q, Tang D*. TuRLK1, a leucine-rich repeat receptor-like kinase, is indispensable for stripe rust resistance of YrU1 and confers broad resistance to multiple pathogens. BMC Plant Biol. 2022; 22(1):280. doi: 10.1186/s12870-022-03679-6.
Niu Y, Huang X, He Z, Zhang Q, Meng H, Shi H, Feng B, Zhou Y*, Zhang J, Lu G, Wang Z, Zhang W, Tang D, Wang M*. Phosphorylation of OsTGA5 by casein kinase II compromises its suppression of defense-related gene transcription in rice. Plant Cell. 2022 doi: 10.1093/plcell/koac164.
Liu, C., Shen, N., Zhang, Q., Qin, M., Cao, T., Zhu, S., Tang, D.,Han, L*.Magnaporthe oryzae Transcription Factor MoBZIP3 Regulates Appressorium Turgor Pressure Formation during Pathogenesis. Int. J. Mol. Sci. 2022, 23,881.doi：10.3390/ijms23020881
Zhao F; Tian S; Li Z; Ye L; Zhuang Y; Wang M; Xie Y; Wu Q; Zou S; Teng W; Tong Y; Tang D; Liu Z; Zhang Y*. Utility of Triti-Map for bulk-segregated mapping of causal genes and regulatory elements in Triticeae.Plant Commun. 2022; 3(4):100304. doi: 10.1016/j.xplc.2022.100304.
Xu, Y., Zou, S., Zeng, H., Wang, W., Wang, B., Wang, H.*, Tang, D.*. A NAC Transcription Factor TuNAC69 Contributes to ANK-NLR-WRKY NLR-Mediated Stripe Rust Resistance in the Diploid Wheat Triticum urartu. Int J Mol Sci. 2022 doi: 10.3390/ijms23010564.
2021
Yu, M. #, Zhou, Z. #, Liu, X., Yin, D., Li, D., Zhao, X., Li, X., Li, S., Chen, R., Lu, L., Yang, D., Tang, D., Zhu, L*. The OsSPK1-OsRac1-RAI1 defense signaling pathway is shared by two distantly related NLR proteins in rice blast resistance. Plant Physiology, 2021 doi: 10.1093/plphys/kiab445.
Xu, R.#, Li, Y#, Liu, C., Shen, N., Zhang, Q., Cao, T., Qin, M., Han, L.*, Tang, D.*. Twinfilin regulates actin assembly and Hexagonal peroxisome 1 (Hex1) localization in the pathogenesis of rice blast fungus Magnaporthe oryzae. Mol Plant Pathol. 2021 doi: 10.1111/mpp.13136.
Wang, W., Liu, N., Gao, C., Rui, L., Jiang, Q., Chen, S., Zhang, Q., Zhong, G., Tang, D.*. The truncated TNL receptor TN2-mediated immune responses require ADR1 function. Plant Journal. 2021 doi: 10.1111/tpj.15463.
Yang, D., Li, S., Xiao, Y., Lu, L., Zheng, Z., Tang, D.,*, Cui, H.*. Transcriptome analysis of rice response to blast fungus identified core genes involved in immunity. Plant Cell & Enviroment. 2021. DOI: 10.1111/pce.14098
Cai, H., Wang, W., Rui L., Han L., Luo, M., Liu, N*, Tang, D.*. The TIR-NBS protein TN13 associates with the CC-NBS-LRR resistance protein RPS5 and contributes to RPS5-triggered immunity in Arabidopsis. Plant Journal . 2021. DOI:10.1111/tpj.15345
Chen, Y., Zhong, G., Cai, H., Chen, R., Liu, N., Wang, W.*, Tang, D.*. A Truncated TIR-NBS Protein TN10 Pairs with Two Clustered TIRNBS-LRR Immune Receptors and Contributes to Plant Immunity in Arabidopsis. Int J Mol Sci. 2021. DOI: 10.3390/ijms22084004
Gao, C., Sun, P., Wang, W., and Tang, D*. Arabidopsis E3 ligase KEG associates with and ubiquitinates MKK4 and MKK5 to regulate plant immunity. J. Integr. Plant Biol. 2021doi: 10.1111/jipb.13007.
2020
Wang, H., Zou, S., Li, Y., Lin，F., Tang, D.*. An ankyrin-repeat and WRKY-domain-containing immune receptor confers stripe rust resistance in wheat. Nature Communications 11, 1353 (2020). doi: 10.1038/s41467-020-15139-6.
Wang, W., Liu, N., Gao C., Cai, H., Romeis, T., and Tang, D*. (2020). The Arabidopsis exocyst subunits EXO70B1 and EXO70B2 regulate FLS2 homeostasis at the plasma membrane. New Phytologist. doi: 10.1111/nph.16515.
Li Y-B, Xu R, Liu C, Shen N, Han L-B*, Tang D* (2020) Magnaporthe oryzae fimbrin organizes actin networks in the hyphal tip during polar growth and pathogenesis. PLoS Pathogens 16(3): e1008437.
Hou H, Fang J, Liang J, Diao Z, Wang W, Yang D, Li S*, Tang D*. OsExo70B1 Positively Regulates Disease Resistance to Magnaporthe oryzae in Rice. Int J Mol Sci. 2020 21(19):E7049. doi: 10.3390/ijms21197049.
Yang D, Li S, Lu L, Fang J, Wang W, Cui H, Tang D*. Identification and Application of the Pigm-1 Gene in Rice Disease-Resistance Breeding. Plant Biol. 2020. doi: 10.1111/plb.13170
Lu L#, Yang D#, Tang D, Li S*, Chen Z*. Transcriptome Analysis of Different Rice Cultivars Provides Novel Insights Into the Rice Response to Bacterial Leaf Streak Infection. Funct Integr Genomics. 2020. doi: 10.1007/s10142-020-00744-x
Wang W., Feng B, Zhou JM*, Tang D*. Plant immune signaling: Advancing on two frontiers. Journal of Integrative Plant Biology. 2020. doi.org/10.1111/jipb.12898 (invited review)
2019
Wang W, Liu N, Gao C, Rui L, Tang D*. The Pseudomonas Syringae Effector AvrPtoB Associates With and Ubiquitinates Arabidopsis Exocyst Subunit EXO70B1. Front Plant Sci. 2019, 10:1027. doi: 10.3389/fpls.2019.01027.
Liu C, Cui D, Zhao J, Liu N, Wang B, Liu J, Xu E, Hu Z, Ren D, Tang D, Hu Y*. Two Arabidopsis Receptor-Like Cytoplasmic Kinases SZE1 and SZE2 Associate with the ZAR1-ZED1 Complex and Are Required for Effector-Triggered Immunity. Molecular Plant. 2019. doi: 10.1016/j.molp.2019.03.012.
Feng, B.* and Tang, D.*. A wheel-of-death in plant spins onto surface：The first view of a plant resistosome structure suggests mechanism of activation and signaling. J Integr Plant Biol. 2019 (commentary)
Wang, Z., Cui, D., Liu, C., Zhao, J., Liu, J., Liu, N., Tang, D., Hu Y.*. TCP transcription factors interact with ZED1‐related kinases as components of the temperature‐regulated immunity. Plant Cell & Evironment. 2019. https://doi.org/10.1111/pce.13515
Zhao Y., Wu G., Shi H., and Tang D.*. RECEPTOR-LIKE KINASE 902 Associates with and Phosphorylates BRASSINOSTEROID-SIGNALING KINASE1 to Regulate Plant Immunity. Molecular Plant. 2019. 12:59-70
2018
Zou, Y., Wang, S., Zhou, Y., Bai, J., Huang, G., Liu, X., Zhang, Y., Tang, D., Lu, D*.
Transcriptional Regulation of the Immune Receptor FLS2 Controls the Ontogeny of Plant Innate Immunity. Plant Cell. 2018, doi: https://doi.org/10.1105/tpc.18.00297
Yan, H.#, Zhao, Y.#, Shi, H., Li, J., Wang, Y., and Tang D*. RASSINOSTEROID- SIGNALING KINASE1 Phosphorylates MAPKKK5 to Regulate Immunity in Arabidopsis. Plant Physiology. 2018, 176: 2991–3002 (#These authors contributed equally)
Zou, S., Wang, H., Li, Y., Kong, Z., Tang D*. The NB-LRR gene Pm60 confers powdery mildew resistance in wheat. New Phytologist. 2018，218: 298–309
Wang, M., Rui, L., Yan, H., Shi, H., Zhao, W., Lin, J.E., Zhang, K., Blakeslee, J.J., Mackey, D., Tang, D., Wei, Z., Wang G.L.. The major leaf ferredoxin Fd2 regulates plant innate immunity in Arabidopsis. Mol. Plant Pathol. 2018, doi: 10.1111/mpp.12621.
2017
Jiang, Y., Wang, W., Xie, Q., Liu, N., Liu, L., Wang, D., Zhang, X., Yang C., Chen, X., Tang, D., Wang E.*. Plants Transfer Lipids to Sustain Colonization by Mutualistic Mycorrhizal and Parasitic Fungi. Science. 2017, 356:1172-1175
Shen, Q., Bourdais, G., Pan, H., Robatzek, S., Tang, D*. The Arabidopsis glycosylphosphatidylinositol-anchored protein LLG1 associates with and modulates FLS2 to regulate innate immunity. PNAS. 2017, 114:5749-5754
Zhang, Y.#, Bai, Y.#, Wu, G., Zou, S., Chen, Y., Gao, C*., Tang, D*. Simultaneous modification of three homoeologs of TaEDR1 by genome editing enhances powdery mildew resistance in wheat.Plant Journal.2017, 91:714-724 (#These authors contributed equally)
Liu, N., Hake, K., Wang, W., Zhao, T., Romeis, T., Tang, D*. CALCIUM-DEPENDENT PROTEIN KINASE5 associates with the truncated NLR protein TIR-NBS2 to contribute to exo70B1-mediated immunity. Plant Cell.2017, 29: 746–759
Tang, D*.,Wang, G., Zhou, J*. Receptor kinases in plant-pathogen interactions: more than pattern-recognition. Plant Cell. 2017, 29: 618–637 (invited review)
Wang, Z., Cui, D., Liu, J., Zhao, J., Liu, C., Xin, W., Li, Y., Liu, N., Ren, D., Tang, D., Hu, Y*. Arabidopsis ZED1-related kinases mediate the temperaturesensitive ntersection of immune response and growth omeostasis. New Phytologist. 2017, 215:711-724.
2016
Tang, D*., Zhou, J*. PEPRs spice up plant immunity. EMBO Journal. 2016, 35:4-5(commentary)
Liu, S., Bartnikas, L.M., Volko, S.M., Ausubel, F.M., Tang, D*. Mutation of the glucosinolate biosynthesis enzyme cytochrome P450 83A1 monooxygenase increases camalexin accumulation and powdery mildew resistance. Front. Plant Sci. 2016, 7:227. doi: 10.3389/fpls.2016.00227
Li, H., Zheng, Q., Pretorius, Z.A. Li, B., Tang, D., Li, Z*.Establishment and characterization of new wheat-Thinopyrum ponticum addition and translocation lines with resistance to Ug99. J Genet Genomics. 2016, 43: 573-575.
2015
Wu, G., Liu S., Zhao, Y., Wang, W., Kong, Z., Tang, D*. ENHANCED DISEASE RESISTANCE4 associates with CLATHRIN HEAVY CHAIN2 and modulates plant immunity by regulating relocation of EDR1 in Arabidopsis. Plant Cell. 2015, 27: 857–873
Zhao, T.#, Rui, L.#, Li J.#, Nishimura M., Vogel J., Liu, N., Liu, S., Zhao, Y., Dangl, J., Tang, D*. A truncated NLR protein, TIR-NBS2, is required for activated defense responses in the exo70B1 mutant. PLoS Genetics. 2015, 11: e1004945 (#These authors contributed equally).
Wang, J., Qu, B., Dou, S., Li, L., Yin, D., Pang, Z., Zhou, Z., Tian, M., Liu, G., Xie, Q., Tang, D., Chen, X., Zhu L. The E3 ligase OsPUB15 interacts with the receptor-like kinase PID2 and regulates plant cell death and innate immunity. BMC Plant Biology, 2015, 15, 1
2014
Zhao, C., Nie, H., Shen, Q,, Zhang, S., Lukowitz, W., Tang, D*. EDR1 physically interacts with MKK4/MKK5 and negatively regulates a MAP kinase cascade to modulate plant innate immunity. PLoS Genetics. 2014, 10: e1004389
Zhao, C., Waalwijk, C., de Wit, P. J., Tang, D., van der Lee, T. Relocation of genes generates non-conserved chromosomal segments in Fusarium graminearum that show distinct and co-regulated gene expression patterns. BMC Genomics. 2014, 15: 191.
2013
Shi, H., Shen, Q., Qi, Y., Yan, H., Nie, H., Chen, Y., Zhao, T., Katagiri, F., Tang, D*. BR-SIGNALING KINASE1 physically associates with FLAGELLIN SENSING2 and regulates plant innate immunity in Arabidopsis. Plant Cell, 2013, 25: 1143-1157
Wang, Y., Yu, B., Zhao, J., Guo, J., Li, Y., Han, S., Huang, L., Du, Y., Hong, Y., Tang, D., Liu, Y. Autophagy contributes to leaf starch degradation. Plant Cell, 2013, 25: 1383-1399
Ling, H.-Q., Zhao, S., Liu, D., J. Wang, Sun, H., Zhang, C., Fan, H., Li, D., Dong, L., Tao, Y., Gao, C., Wu., H., Li, Y., Cui, Y., Guo, X., Zheng, S., Wang, B., Yu, K., Liang, Q., Yang, W., Lou, X., Chen, J., Feng, M., Jian, J., Zhang, X., Luo, G., Jiang, Y., Liu, J., Wang, Z., Sha, Y., Zhang, B., Wu, H., Tang, D., Shen, Q., Xue, P., Zou, S., Wang, X., Liu, X., Wang, F., Yang, Y., An, X., Dong, Z., Zhang, K., Zhang, X., Luo, M.-C., Dvorak, J., Tong, Y., Wang, J., Yang, H., Li, Z., Wang, D., Zhang, A., Wang, J. Draft genome of the wheat A-genome progenitor Triticum urartu. Nature, 2013, 496: 87-90.
Wu, T., Tang, D., Chen W., Huang H., Wang R., Chen Y. Expression of antimicrobial peptides thanatin(S) in transgenic Arabidopsis enhanced resistance to phytopathogenic fungi and bacteria. Gene. 2013, 527:235-242.
Shi, H., Yan, H., Li, J., Tang, D*. BSK1, a receptor-like cytoplasmic kinase, involved in both BR signaling and innate immunity in Arabidopsis. Plant Signal Behav. 2013, 8: e24996
Wu, T., Chen, Y., Chen, W., Zou, S., Zhang, Y., Lin, Y., Liang, Z., Tang, D. Transgenic expression of an insect diapause-specific peptide (DSP) in Arabidopsis resists phytopathogenic fungal attacks. Eur J Plant Pathol. 2013. 137:93-101
Guo, C. #, Wu, G. #, Xing, J., Li, W., Tang, D*., Cui B*. A mutation in a coproporphyrinogen III oxidase gene confers growth inhibition, enhanced powdery mildew resistance and powdery mildew-induced cell death in Arabidopsis. Plant Cell Rep, 2013, 32:687–702. (#These authors contributed equally)
Zhao, C., Waalwijk, C., de Wit, P. J., Tang, D., van der Lee, T. RNA-Seq analysis reveals new gene models and alternative splicing in the fungal pathogen Fusarium graminearum. BMC Genomics, 2013, 14: 21.
2012
Nie, H., Zhao, H., Wu, G., Wu Y., Chen, Y., Tang, D*. SR1, a Calmodulin binding transcription factor, modulates plant defense and ethylene-induced senescence by directly regulating NDR1 and EIN3. Plant Physiology. 2012, 158: 1847-1859
Pan, H.,. Li, S., Tang, D*. The THO/TREX complex functions in disease resistance in Arabidopsis. Plant Signal Behav. 2012, 7: 422-424
Pan, H.,. Li, S., Tang, D*. HPR1, a component of the THO/TREX complex, plays an important role in disease resistance and senescence in Arabidopsis. Plant Journal. 2012, 69: 831-843
2011
Wang, Y.,. Wu, Y., Tang, D*.. The autophagy gene, ATG18a, plays a negative role in powdery mildew resistance and mildew-induced cell death in Arabidopsis. Plant Signal Behav. 2011, 6: 1408-1410
Zhao, C., Waalwijk, C., de Wit, P., van der Lee, T., Tang D*. EBR1, a novel Zn2Cys6 transcription factor, affects virulence and apical dominance of hyphal tip in Fusarium graminearum. Mol Plant Microbe Interact. 2011, 24: 1407-1418
Wang, Y., Nishimura, M.T., Zhao, T., Tang, D*. ATG2, an autophagy-related protein, negatively affects powdery mildew resistance and mildew-induced cell death in Arabidopsis. Plant Journal. 2011, 68: 74-87
Nie, H., Wu, Y., Yao, C., Tang, D*. Suppression of edr2-mediated powdery mildew resistance, cell death and ethylene-induced senescence by mutations in ALD1 in Arabidopsis. J Genet Genomics. 2011, 38: 137-148.
2010及以前
Ge, L., Peer, W., Robert, S., Swarup, R., Ye, S., Prigge, M., Cohen, J.D., Friml, J., Murphy, A., Tang, D., Estelle. M. Arabidopsis ROOT UVB SENSITIVE2/WEAK AUXIN RESPONSE1 Is Required for Polar Auxin Transport. Plant Cell. 2010, 22: 1749-1761
Gou M., Su N., Zheng J., Huai, J., Wu G., Zhao J, He, J., Tang, D., Yang, S., Wang G. An F-box gene, CPR30, functions as a negative regulator of the defense response in Arabidopsis. Plant Journal. 2009, 60, 757–770
Tang, D.*, Simonich, M.T., Innes R. W. Mutations in LACS2, a Long-Chain Acyl-Coenzyme A Synthetase, Enhance Susceptibility to Avirulent Pseudomonas syringae But Confer Resistance to Botrytis cinerea in Arabidopsis. Plant Physiology. 2007, 144:1093-1103
Tang, D, Jules A., Frye C. A., Innes R. W. A Mutation in the GTP hydrolysis site of Arabidopsis Dynamin-Related Protein 1E Confers Enhanced Cell Death in Response to Powdery Mildew Infection. Plant Journal. 2006, 47:75-84
Tang, D., Ade, J., Frye C.A., Innes R. W. Regulation of Plant Defense Responses in Arabidopsis by EDR2, a PH and START Domain-Containing Protein. Plant Journal. 2005, 44:245-257
Tang, D., Christiansen, K. M., Innes R. W. Regulation of Plant Disease Resistance, Stress Responses, Cell Death and Ethylene Signaling in Arabidopsis by the EDR1 Protein Kinase. Plant Physiology. 2005, 138:1018-1026
Chen, Z., Kloek, A.P., Cuzick, A., Moeder, W., Tang, D., Innes R.W., Klessig D.F., McDowell J.M., Kunkel B.N. The Pseudomonas syringae type III effector AvrRpt2 functions downstream or independently of SA to promote virulence on Arabidopsis thaliana. Plant Journal. 2004, 37:494-504.
Tang, D. and Innes, R. W . Overexpression of a kinase-deficient form of the EDR1 gene enhances powdery mildew resistance and ethylene-induced senescence in Arabidopsis. Plant Journal. 2002, 32: 975-83
Frye#, C.A., Tang, D.#, Innes R.W. Negative regulation of defense responses in plants by a conserved MAPKK kinase. Proc. Natl. Acad. Sci. USA. 2001, 98: 373-378. (#These authors contributed equally)
Chen, W., Tang, D., Suo, J., Zhang, Y., Xue, Y. Expressional profiling of genes related to pollination and fertilization in rice. C. R. Acad. Sci. Ser. III. 2001. 324:1111-1116
Tang, D., Wu, W., Li, W., Lu H., Worland, AJ. Mapping of QTLs conferring resistance to bacterial leaf streak in rice. Thero. Appl. Genet. 2000, 101: 286-291
Wu, W., Li, W., Tang, D., Lu, H., Worland, A. J. Time-related mapping of QTLs underlying tiller number in rice. Genetics 1999, 151(1):297-303
Zhu, J. H., Stephenson, P., Laurie, D. A., Li, W., Tang, D., Gale, M. D. Towards rice genome scanning by map-based AFLP fingerprinting. Mol. Gen. Genet. 1999, 261:184-195.
Xue, Y., Tang, D., Zhang, Y. and Li, W. (1998) Isolation of candidate R disease resistance genes from rice. Chin. Sci. Bull. 43:497-500